Which of the following symptoms is NOT associated with Neuroleptic Malignant Syndrome?

Neuroleptic Malignant Syndrome (NMS) is a serious and potentially life-threatening reaction often associated with the use of antipsychotic medications. The core symptoms of NMS include severe muscle rigidity, hyperthermia (fever), autonomic instability, and altered mental status.

Among these symptoms, fever, extreme rigidity, and tachycardia are highly characteristic of NMS. Fever indicates the body’s response to stress and is commonly elevated in NMS cases. Extreme rigidity refers to the severe muscle stiffness that can severely limit movement and is a hallmark symptom of this syndrome. Tachycardia, or elevated heart rate, occurs as part of the autonomic instability seen in NMS.

Low blood pressure, while it can occur in various medical conditions, is not a typical symptom associated with Neuroleptic Malignant Syndrome. In fact, individuals with NMS often experience elevated blood pressure rather than low. Therefore, the option describing low blood pressure is correct as it does not align with the primary symptomatology of NMS, distinguishing it from the other symptoms listed.